Pancreatic metastases - likely from renal cell carcinoma

Case contributed by Dominik Maas , 30 Nov 2015
Diagnosis certain
Changed by Ian Bickle, 18 Jan 2016

Updates to Case Attributes

Title was changed:
Pancreatic metastases: - likely from renal cell carcinoma
Presentation was changed:
The PatientThis patient presented itself with abdominal pain of the upper quadrant and darkend urindark urine. Ultrasonic imaging showed a slight dilatation of the common hepatic duct (CHD) of max.maximum of 8 mm. The ERCP showed a distal carinoma-like CHD-stenosis, a stent was applied. History withPast history of renal cell carinomacarcinoma (RCC) of the right kidney with explantationnephrectomy on 01/2013 pT3b Nx Mx V1 R1.Lung-metastases 05/2014. Start of chemotherapy with Pazopanib from 05-08/08/2014.
Body was changed:

These pancreatic metastases are only been shownseen in the arterial phase. A single phase protocol would have missed these lesions.

  • -<p>These pancreatic metastases are only been shown in the arterial phase. A single phase protocol would have missed these lesions.</p>
  • +<p>These pancreatic metastases are only seen in the arterial phase. A single phase protocol would have missed these lesions.</p>

Updates to Study Attributes

Findings was changed:

Hyperdense pancreatic metastases only evident in the arterial phase.

Images Changes:

Image CT (C+ arterial phase) ( update )

Description was changed:
1. At least five different pancreatic lesions with contrast affinity in the arterial phase in the head, corpus and cauda. The biggest is located in the pancreatic head next to the common hepatic duct. 2. A stent is applied into the CHD and a small air bubble ishas collected within the gall bladder. 3. The right kidney is missing. Multiple renal zystscysts of the left kidney, Bosniak I.

Image CT (C+ portal venous phase) ( update )

Description was changed:
The pancreatic metastases are isodensisodense to the normal pancreatic parenchyma.

Image CT (C+ portal venous phase) ( update )

Description was changed:
The pancreatic metastases are isodensisodense to the normal pancreatic parenchyma.

Updates to Quizquestion Attributes

Question was changed:
What are the most likely metastases ofto the pancreas?
Answer was changed:
Metastases in the pancreas are not very likelycommon. In most of the cases they come from melanoma (most of the times hyperdenshyperdense in all phases), lung-, mammabreast, ovarial-carcinomaovary and of causethe kidney and adrenal glands.

Updates to Quizquestion Attributes

Question was changed:
What is the differential diagnosediagnosis of aan enhanced lesion in a nativnative scan?
Answer was changed:
A hemorrhagic metastasis or more likely a melanoma metastasis could show a hypertenuationbe of hyperattenuation in a nativnative scan. Therefore only the arterial phase could give you not enough information to differentiate the lesions.

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