Panophthalmitis complicated by optic neuritis

Case contributed by Ammar Haouimi
Diagnosis almost certain

Presentation

Purulent discharge from the right eye with pain and extensive orbital and periorbital oedema. An intraocular lens implant was performed on the same side one year ago.

Patient Data

Age: 90 years
Gender: Female
This study is a stack
Axial
T1
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Axial
FLAIR
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Coronal
T2
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Axial T2
fat sat
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Coronal T2
fat sat
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Axial T1
fat sat
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Axial T1
C+ fat sat
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Coronal T1
C+ fat sat
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Axial
T1 C+
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Coronal
T1 C+
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Info

The MRI sequences demonstrate:

  • areas within the vitreous chamber of the right globe of intermediate signal on T1, intermediate to high signal on FLAIR/T2 with no enhancement, representing most likely vitreal exudates
  • diffuse smooth uveal/scleral thickening with enhancement
  • retinal detachment
  • swelling with enhancement of the retrobulbar intra-orbital segment of the optic nerve and surrounding nerve sheath (optic neuritis)
  • extensive intraorbital/peribulbar fat stranding with enhancement
  • abnormal swelling with enhancement of the orbital muscles
  • oedematous infiltration with enhancement of the periorbital soft tissues
  • the cavernous sinuses are patent

Note a slow flow within the left transverse/sigmoid sinuses and internal jugular vein mimicking thrombosis. Their patency is confirmed on enhanced sequences.

Case Discussion

MRI features are most consistent with a right panophthalmitis with associated optic neuritis

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