Papillary thyroid carcinoma

Case contributed by A.Prof Frank Gaillard


Case Discussion

50 year old patient with a previous papillary carcinoma of the thyroid on left treated with hemithyroidectomy, now presents with a new right sided nodule.


Smears reveal numerous cohesive fragments of follicular epithelium present mainly as loosely cohesive sheets attached to delicate branching capillaries or as densely cellular syncytial aggregates. Most of the follicular cells have ovoid, mildly pleomorphic irregular nuclei with fine chromatin and indistinct micronuclei. Many nuclei have nuclear grooves and a minor portion show nuclear inclusions. Some polygonal cells with dense "squamoid" cytoplasm are present. Colloid is scanty. A few fragments of follicular epithelium have follicular cells with scant cytoplasm, round nuclei and compact chromatin. This may represent sampling of adjacent benign epithelium. The features are sufficient for a diagnosis of papillary thyroid carcinoma. 

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Case information

rID: 9478
Published: 22nd Apr 2010
Last edited: 13th Aug 2019
System: Head & Neck
Inclusion in quiz mode: Included

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