Papillary thyroid carcinoma with neck node metastases

Case contributed by Frank Gaillard
Diagnosis certain

Note: This case has been tagged as "legacy" as it no longer meets image preparation and/or other case publication guidelines.

Cystic nodes on the right side of the neck with a heterogeneous thyroid gland. Probable vertebral body metastasis also (axial bone window). 

Case Discussion

Histology

Microscopic Description: 

The fine needle aspirate from the neck region is a cellular aspirate showing clusters of atypical follicular epithelial cells and inspissated colloid. Some of the clusters are associated with colloid. No definite papillary fragments are seen. However, there is an occasional stromal fibrovascular core identified. 

Individual clusters of epithelial cells show cells with irregular nuclear outlines and nuclear grooves. A focal intranuclear inclusion is seen. There is crowding and overlapping of nuclei present. Some of the clusters have a Hurthle cell appearance with more abundant cytoplasm.

FNA Final Diagnosis: Papillary carcinoma of thyroid

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