Particle disease - total hip replacement
Presentation
Pain in right hip and knee 10 years after total hip replacement.
Patient Data
Age: 75 years
Gender: Female
Case Discussion
Released cement particles trigger the release of inflammatory mediators. Local accumulation of inflammatory mediators produces a local giant cell granulomatous reaction and leads to osteolysis and formation of cystic change in adjacent bone. This process is referred to as particle disease, and is a significant cause of revision surgery.