Particle disease - total hip replacement

Case contributed by Dr Maarten Borg


Pain in right hip and knee 10 years after total hip replacement.

Patient Data

Age: 75 years
Gender: Female

To be added

Case Discussion

Released cement particles trigger the release of inflammatory mediators. Local accumulation of inflammatory mediators produces a local giant cell granulomatous reaction and leads to osteolysis and formation of cystic change in adjacent bone. This process is referred to as particle disease, and is a significant cause of revision surgery. 

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Case information

rID: 13870
Published: 26th May 2011
Last edited: 4th Sep 2020
Inclusion in quiz mode: Included