Pathogenesis of penetrating atherosclerotic ulcer (illustration)

Case contributed by Vincent Tatco

This stack of images shows the formation of a penetrating atherosclerotic ulcer (PAU). A penetrating atherosclerotic ulcer forms when atheromatous plaques erode. The ulcerating atherosclerotic lesion penetrates the intima and progresses into the media. When the ulcer reach the media, it may also injure the vasa vasorum that may lead to intramural hematoma formation.

Case Discussion

This diagram depicts the formation of a penetrating atherosclerotic ulcer, which is an ulcerating atherosclerotic lesion that involves the intimal and medial layers of the aortic wall. It is one of the possible causes of an acute aortic syndrome.

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