Periosteal osteosarcoma

Case contributed by Dr Subash Thapa


23 year old male with pain and swelling of the right thigh.

Patient Data

Age: 23 years
Gender: Male

There is a broad based eccentric lytic lesion in the diaphysis of the right midshaft of femur involving the lateral cortex with periosteal reaction. There is also evidence of thickening of the adjacent cortex. Soft tissue opacity mass is seen anteriorly, suggesting an extraosseous soft tissue component. 

Case Discussion

Biopsy reveals Intermediate to high grade osteosarcoma with prominent cartilaginous component.

Periosteal osteosarcoma arises from the inner layer of periosteum (parosteal osteosarcoma arises from outer layer) and contain large amount of cartilaginous matrix.

Periosteal osteosaraoma are worse than parosteal osteosarcoma but better than conventional osteosarcoma in terms of prognosis. 

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Case information

rID: 40937
Case created: 8th Nov 2015
Last edited: 22nd Dec 2016
Inclusion in quiz mode: Included

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