Presentation
Buttock and lower back pain.
Patient Data
Age: 24
Gender: Male
From the case:
Peripheral primitive neuroectodermal tumor
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Heterogeneous fluid signal ring enhancing lytic lesion involving right sacral ala and body of S1 vertebrae are seen.
Case Discussion
Bone is a rare location and there have been few reports of osseous PNETs in the literature. Osseous PNETs may be seen in any bone in every age groups, but mainly affect children and adolescents with male predominance.
Our case was pathologically proven. The neoplastic cells express immunoreactivity as below:
- Positive:
- Neuron Specific Enolase
- Mi2
- Ki67(30%)
- Negative:
- Leukocyte Common antigen
- Myogenin
- Desmin
- CD20
Diagnosis: Immunohistochemical expression consistent with "primitive neuroectodermal tumor".
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