Peripheral primitive neuroectodermal tumor

Case contributed by Dr Bahman Rasuli


Buttock and lower back pain.

Patient Data

Age: 24
Gender: Male

Heterogeneous fluid signal ring enhancing lytic lesion involving right sacral ala and body of S1 vertebrae are seen.

Case Discussion

Bone is a rare location and there have been few reports of osseous PNETs in the literature. Osseous PNETs may be seen in any bone in every age groups, but mainly affect children and adolescents with male predominance.

Our case was pathologically proven. The neoplastic cells express immunoreactivity as below:

  • Positive:
    • Neuron Specific Enolase
    • Mi2
    • Ki67(30%)
  • Negative:
    • Leukocyte Common antigen
    • Myogenin
    • Desmin
    • CD20

Diagnosis: Immunohistochemical expression consistent with "primitive neuroectodermal tumor". 

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Case information

rID: 62104
Published: 5th Aug 2018
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included
Institution: Jame Jam Imaging Center

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