Periventricular leukomalacia

Case contributed by Bahman Rasuli
Diagnosis almost certain

Presentation

Intellectual disability and seizures.

Patient Data

Age: 8 years
Gender: Male
mri
This study is a stack
Axial
T1
This study is a stack
Axial
T2
This study is a stack
Axial
FLAIR
This study is a stack
Coronal
T1
This study is a stack
Coronal
T2
This study is a stack
Sagittal
T2
This study is a stack
Axial
ADC
This study is a stack
Axial
DWI
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Info

The MRI sequences demonstrate:

  • ventriculomegaly with wavy and irregular lateral contours

  • loss of periventricular white matter with increased signal on FLAIR and T2 sequences

  • thinning of the corpus callosum

Case Discussion

MRI features are most consistent with end-stage periventricular leukomalacia (PVL).

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