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Final Diagnosis: Pheochromocytoma
Left adrenal gland, laparoscopic adrenalectomy showing:
- Pheochromocytoma, measuring 3 cm in maximum dimension.
- No definite evidence of lymphovascular invasion.
Final Diagnosis Comment:
The majority of the tumour is surrounded by a fibrous capsule, which is very attentuated in areas but tumour does not appear to extend to the inked external surface. The tumour shows moderate cytologic atypia with very scant mitotic activity. The tumour shows focal sustentacular pattern of S100 positivity. It is also positive for synaptophysin and neuron specific enolase.
Please note that there is no reliable histological criteria for distinguishing benign versus malignant pheochromocytoma. Clinical correlation and follow-up is recommended.
The specimen is received in a single container labeled with the patient's name and "left adrenal mass" and consists of two fragments of an adrenalectomy specimen. One measures 3 x 3.5 x 3 cm, while the second measures 3.5 x 2 x 1 cm.