Pituitary adenoma: null cell type with necrosis

Case contributed by A.Prof Frank Gaillard

Large sellar/suprasellar mass with intrinsic high T1 signal, cystic signal change and post contrast enhancement. 

Post operative imaging shows debulking of the tumour. 

Case Discussion

Null cell adenoma with incomplete resection.

Final Diagnosis:

Pituitary tumor: Pituitary adenoma, null cell type.

Gross Description:

Specimen is received in one container labelled with patient's demographics and LARGE PITUITARY TUMOUR and consists of four small hemorrhagic tan tissue fragments aggregating to 6 x 4 x 2 cm.

The second specimen is received in a plastic container labelled with the patient's demographics and SUPRASELLAR TUMOUR. It consists of an aggregate of tan and hemorrhagic tissue fragments measuring 5 x 3.5 x 0.4 cm.

Microscopic Description:

Sections show fragments of pituitary adenoma: tumour cells are arranged in trabeculae, acinar structures and diffuse sheets. Immunohistochemical studies show negative immunoreactivity for ACTH, GH, LH, FSH, TSH and prolactin.

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Case information

rID: 4976
Case created: 12th Nov 2008
Last edited: 14th Nov 2017
Inclusion in quiz mode: Included

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