Pituitary apoplexy

Case contributed by Dalia Ibrahim
Diagnosis almost certain

Presentation

Headache and ophthalmoplegia. Increased prolactin levels.

Patient Data

Age: 20 years
Gender: Female
mri
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T2
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T1
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Coronal
T1
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Coronal
T2
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T2
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Coronal T1
C+-Dynamic
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Coronal
T1 C+
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Sagittal
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A sellar space occupying lesion mainly on the right side. It elicits cystic signal on T2 with internal haemorrhagic signal eliciting high signal on T1 and low signal on T2 WI. It shows marginal post-contrast enhancement. It shows upper contour bulge into the suprasellar region and causes mild sagging of the sellar floor and deviation of the pituitary stalk to the left side. No cavernous sinus invasion.

6 months later

mri
This study is a stack
Axial
T2
This study is a stack
Sagittal
T1
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Coronal
T1
This study is a stack
Sagittal
T2
This study is a stack
Coronal
T2
This study is a stack
Coronal T1
C+-Dynamic
This study is a stack
Sagittal
T1 C+
This study is a stack
Coronal
T1 C+
Show annotations
Download
Info

Follow-up MRI 6 months after medical treatment showed marked regression in size of the pituitary cystic lesion with resolution of the internal haemorrhagic signal. Currently, small intra-pituitary cystic lesion elicits low signal on T1 WI and high signal on T2 and appears less enhancing on the post-contrast series.

Case Discussion

Pituitary apoplexy is an acute clinical syndrome caused by either haemorrhage or infarction of the pituitary gland. Although variable, it typically comprises of headache, visual deficits, ophthalmoplegia, and altered mental status. An existing pituitary macroadenoma is usually present (60 - 90%) but it can occur with healthy glands in few isolated cases.

Pituitary apoplexy may also occur during pregnancy or post-partum period (Sheehan syndrome).

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