Pituitary macroadenoma - GH

Case contributed by A.Prof Frank Gaillard

Presentation

Adult patient presenting with a homonymous bitemporal hemianopia.

Patient Data

Age: Adult

MRI brain

Modality: MRI

MRI of the pituitary demonstrating a large mass extending into the suprasellar cistern and compressing the optic chiasm. Note the invasion into the left cavernous sinus with encasement of the ICA.

This patient went on to have transphenoidal surgery. 

Histology

Microscopic Description: Sections show pieces of a pituitary adenoma, and fragments of neurohypophysis. Focal microcysts are seen. The tumor cells are immunoreactive for growth hormone, and are immuno-negative for LH, TSH and FSH. Rare cells display immunoreactivity for ACTH and prolactin.

Final Diagnosis: Pituitary macroadenoma, showing growth hormone immunoreactivity.

Case Discussion

This case demonstrates appearances of a sizable pituitary macroadenoma. 

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Case Information

rID: 5277
Case created: 29th Dec 2008
Last edited: 7th Dec 2015
Inclusion in quiz mode: Included

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