Pleomorphic xanthoastrocytoma

Case contributed by Dr Mohammad A. ElBeialy


30 Years old female with 2 years history of seizures and chronic headache.

Patient Data

Age: 30
Gender: Female
Modality: MRI

A right temporal lobe cortical based lobulated cystic mass lesion with enhancing mural nodule.

The lesion measures 17 X 17 X 13 mm in its main CC and axial dimensions.
The solid nodule of the lesion shows isointense T1 and T2 signal with intense homogenous post-contrast enhancement. The cystic component of the lesion shows low T1 and high T2 signal with marginal post-contrast enhancement. The lesion is associated with mild vasogenic brain oedema with mild compression of the right lateral ventricle’s temporal horn and some effacement of cortical sulci.


A right temporal based cystic mass lesion with enhancing mural nodule, mostly representing pleomorphic xanthoastrocystoma (PXA). The differential includes is ganglioglioma or dysembryonic neuro-epithelial tumour (DNET).

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Case Information

rID: 23407
Case created: 12th Jun 2013
Last edited: 25th Feb 2016
Inclusion in quiz mode: Included

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