Pleural mesothelioma

Case contributed by Bruno Di Muzio
Diagnosis almost certain


Chest pain and subacute shortness of breath.

Patient Data

Age: 75 years
Gender: Male



There is diffuse soft tissue pleural thickening with nodularity in the left hemithorax highly suggestive of primary pleural malignancy. There is a small pleural effusion at the lung base with evidence of chronicity and left lung volume loss.

Right lung and pleural space are clear.

Enlarged cardiophrenic and left mediastinal lymph nodes are likely involved.

There is no clear fat planes between the pleural malignancy and the distal aortic arch and descending thoracic aorta, as well as no clear planes with the pericardium, concerning for invasion.

Case Discussion

Classic presentation and imaging appearances of pleural mesothelioma, which was later confirmed on biopsy.

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