Patient with a long (38 years) history of slowly growing masses on the neck with multiple resections since then.
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There are multiple confluent enhancing lesions predominantly on the left side of the neck and in the upper mediastinum which are responsible for an asymetrical stenosis of the pharynx and trachea. Notice the target sign on T2 sequence typical for neurofibromas.
This patient underwent several surgical resections throughout last decades (and also recent chemotherapy treatment) with histologically confirmed diagnosis of plexiform neurofibroma (see article Neurofibromatosis type I). There were also signs of malignant transformation documented.