Polymicrogyria

Case contributed by Dr Fazel Rahman Faizi

Presentation

Seizures and left lower limb weakness.

Patient Data

Age: 6 year-old
Gender: Male
MRI

The right cerebral hemisphere is small compared to the left side, showing abnormal sulcation and dysmorphic cortex. There is right perisylvian polymicrogyria evident by deep infoldings and abnormal thickening of the cortex involving the right superolateral frontal, parietal and temporal lobes. There is relative smaller size of the right caudate nucleus with ex-vacuo dilatation of frontal and occipital horns of the right lateral ventricle. Incidental cavum septum pellucidum and verge.

Case Discussion

Polymicrogyria is a cortical developmental malformation that the process of normal cortical development is disrupted during the late stages of neuronal migration and cortical organization. Clinically, Patients with polymicrogyria may present with developmental delay, focal neurologic deficit, or epilepsy, depending on the part of the brain involved.

Dr. Farhad Farzam has also contributed to this case.

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Case information

rID: 67168
Published: 22nd Mar 2019
Last edited: 25th Mar 2019
Inclusion in quiz mode: Included
Institution: French Medical Institute for Mothers and children

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