Posterior cortical atrophy

Case contributed by A.Prof Frank Gaillard

Presentation

Fairly rapid decrease in cognitive function with difficulty in performing visual tasks.

Patient Data

Age: 50 years
MRI

Bilateral volume loss is primarily seen in the parietal lobes. The temporal lobes, including mesial temporal structures, are relatively spared. No abnormal diffusion restriction or susceptibility-induced signal loss. 

Nuclear medicine

PET with neurostat

PET with Neurostat maps demonstrate reduced activity/uptake in the parietal lobes best appreciated on the medial interhemispheric projection on neurostat. 

Nuclear medicine

SPECT with neurostat

SPECT with Neurostat maps demonstrate reduced activity/uptake in the parietal lobes best appreciated on the medial interhemispheric projection on neurostat. 

Case Discussion

The patient also had an amyloid PET (not shown) that was strongly positive, supportive of the diagnosis of Alzheimer's disease. Posterior variant is also clinically supported by primarily visuospatial association and parietal deficits, Balint's and Gerstmann's syndrome, etc.

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Case information

rID: 63646
Published: 16th Oct 2018
Last edited: 9th Nov 2018
Inclusion in quiz mode: Included

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