Presentation
Fairly rapid decrease in cognitive function with difficulty in performing visual tasks.
Patient Data
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Bilateral volume loss is primarily seen in the parietal lobes. The temporal lobes, including mesial temporal structures, are relatively spared. No abnormal diffusion restriction or susceptibility-induced signal loss.
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PET with Neurostat maps demonstrate reduced activity/uptake in the parietal lobes best appreciated on the medial interhemispheric projection on neurostat.
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SPECT with Neurostat maps demonstrate reduced activity/uptake in the parietal lobes best appreciated on the medial interhemispheric projection on neurostat.
Case Discussion
The patient also had an amyloid PET (not shown) that was strongly positive, supportive of the diagnosis of Alzheimer's disease. Posterior variant is also clinically supported by primarily visuospatial association and parietal deficits, Balint's and Gerstmann's syndrome, etc.
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