Posterior fossa ependymoma

Case contributed by Hani Makky Al Salam
Diagnosis almost certain

Presentation

Headaches.

Patient Data

Age: Child
Gender: Male

MRI brain

mri

A very large rounded heterogenous tumor is present in the fourth ventricle, bulging inferiorly through the foramina of Luscka and Magendie. It is hyperintense on T2 weighted images,  low on T1 weighted images, with heterogeneous contrast enhancement and has intermediate restricted diffusion on ADC. A ventricular shunt has been inserted through the right frontal lobe. 

Case Discussion

This case illustrates the difficulty in categorically distinguishing medulloblastomas from ependymomas. 

This child went on to have a craniotomy confirming the diagnosis of a posterior fossa ependymoma.

Note: as molecular profiling is unavailable in this case, it would have the diagnosis of posterior fossa ependymoma not otherwise specified (NOS). 

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