Posterior reversible encephalopathy syndrome (PRES)

Case contributed by Magdi Mahsoub
Diagnosis probable

Presentation

Known case of eclampsia, presented with multiple seizures.

Patient Data

Age: 25 years
Gender: Female
This study is a stack
Axial
T1
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Axial
T2
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Axial
FLAIR
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Axial
DWI
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Axial
ADC
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Sagittal
T1
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Coronal
T2
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Coronal
FLAIR
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Info

Bilateral nearly symmetrical mainly cortical/subcortical T2/FLAIR high signal at the frontal, parietal, occipital, and temporal lobes. Also, similar signal intensity is seen at the deep gray nuclei, brainstem, and both cerebellar hemispheres with multiple bilateral supratentorial and infratentorial scattered areas of diffusion restriction (high signal on DWI and low signal on ADC).

Case Discussion

Posterior reversible encephalopathy syndrome (PRES), also known as reversible posterior leukoencephalopathy syndrome (RPLS), is a neurological disorder characterized by a range of symptoms including headaches, seizures, altered mental status, and visual disturbances. It is typically associated with acute hypertension, though it can also occur in the context of other conditions such as eclampsia, renal failure, immunosuppressive therapy, or autoimmune diseases.

PRES is a potentially reversible condition that requires prompt recognition and treatment to prevent permanent neurological damage. Early diagnosis through clinical evaluation and imaging, along with aggressive management of underlying causes, is essential for a favorable outcome.

In our case, the associated clinical data of eclampsia with multiple seizures and radiological features are characteristic of posterior reversible encephalopathy syndrome (PRES).

Unfortunately, there is no available further imaging follow-up.

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