Primary breast lymphoma
Citation, DOI & case data
A single female patient, previously healthy, complaining of right breast lump that causing pain, no other associated symptoms or family history.
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- Right breast enhanced mass lesion, measures about 4.5 x 8 cm inseparable from the overlying skin and glandular element, however, no evidence of chest wall or skin invasion.
- No evidence of widespread disease.
This is a single female patient, previously healthy, complaining of right breast lump that causing pain with no other associated symptoms or family history. she did FDJ PET scan and showed hypermetabolic activity mass lesion at the right breast with satellite lesion.
The subjected to breast biopsy and revealed DLBCL of non-Hodgkin's lymphoma (NHL).
Primary breast lymphoma is less common than secondary lymphoma and is typically a B cell type of non-Hodgkin's lymphoma (NHL). Primary non-Hodgkin lymphoma of the breast represents only ~0.25% (range 0.12-0.53%) of all reported malignant breast tumors.
For a tumor to be labeled as a primary breast lymphoma it is required to fulfill the following criteria and all are met in our case ;
- The disease should be in the breast or in close proximity to breast tissue.
- No evidence of widespread disease should be there
- No previous history of lymphoma
- Ipsilateral lymph nodes may be involved if developing simultaneously with primary breast tumor.
- Shim E, Song SE, Seo BK, Kim YS, Son GS. Lymphoma affecting the breast: a pictorial review of multimodal imaging findings. (2013) Journal of breast cancer. 16 (3): 254-65. doi:10.4048/jbc.2013.16.3.254 - Pubmed
- Surov A, Holzhausen HJ, Wienke A, Schmidt J, Thomssen C, Arnold D, Ruschke K, Spielmann RP. Primary and secondary breast lymphoma: prevalence, clinical signs and radiological features. (2012) The British journal of radiology. 85 (1014): e195-205. doi:10.1259/bjr/78413721 - Pubmed