Primary CNS lymphoma

Case contributed by Dr Mohamed Samy


Headache and seizures.

Patient Data

Age: 35
Gender: Male

A butterfly-like lesion involving the body of the corpus callosum. Eliciting high signal at T2 and FLAIR WIs and low signal at T1 WIs with homogeneous contrast uptake Mild surrounding edema. No cystic changes. No other similar lesions.

Right basal ganglia and left subinsular cystic changes without enhancement most probably represent encephalomalacia.

Case Discussion

The differential diagnosis for this case includes:

  • glioblastoma, less likely due to no cystic changes and mild edema
  • multiple sclerosis, less likely due to the absence of other lesions
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Case information

rID: 62064
Published: 4th Aug 2018
Last edited: 28th Nov 2019
Inclusion in quiz mode: Included
Institution: Private practice

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