Primary CNS lymphoma

Case contributed by Mohamed Abdalla
Diagnosis possible

Presentation

Headache and seizures.

Patient Data

Age: 35
Gender: Male
mri

A butterfly-like lesion involving the body of the corpus callosum. Eliciting high signal at T2 and FLAIR WIs and low signal at T1 WIs with homogeneous contrast uptake Mild surrounding edema. No cystic changes. No other similar lesions.

Right basal ganglia and left subinsular cystic changes without enhancement most probably represent encephalomalacia.

Case Discussion

The differential diagnosis for this case includes:

  • glioblastoma, less likely due to no cystic changes and mild edema
  • multiple sclerosis, less likely due to the absence of other lesions

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