Primary CNS lymphoma - involving the septum pellucidum

Case contributed by Dr Bruno Di Muzio


40 years old female, HIV positive with AIDS. Previous (another service) diagnosis of CNS lymphoma with MRI and contrasted CT, both not available for comparison. A non-contrast CT study was requested.

Patient Data

Age: 42
Gender: Female

There is an extensive hyperattenuating mass enlarging the septum pellucidum.

Case Discussion

The images show a hyperattenuating mass enlarging septum pellucidum that is in keeping with the known diagnosis of CNS lymphoma. The hyper attenuation of the mass is consistent with the high cellularity present in lymphoma. 

There is a strong association of primary CNS lymphoma (PCNSL) with HIV/AIDS and immunocompromised states, with approximately 2 to 6% of patients with HIV developing PCNSL.

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Case information

rID: 13107
Published: 1st Mar 2011
Last edited: 16th May 2018
Inclusion in quiz mode: Excluded

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