Primary sclerosing cholangitis

Case contributed by Mahomed A. Osman


Recurrent cholangitis. Ulcerative colitis.

Patient Data

Age: 45 years
Gender: Male

The bile ducts show alternating segments of constriction and dilatation forming a 'beaded' appearance. This is consistent with primary sclerosing cholangitis.

Case Discussion

Primary sclerosing cholangitis is an autoimmune disorder that causes inflammation of the intra and extrahepatic bile ducts, ultimately leading to their obstruction. This may go on to cause hepatic failure. Around 80% of people with PSC have ulcerative colitis.

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