Progressive primary aphasia
60 year old female patient presented with vague neurology including difficulty with speech.
CT Brain (selected image)
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Left perisylvian atrophy may represent progressive primary aphasia.
Primary progressive aphasia (PPA) is the umbrella term for the language-variant fronto-temporal dementias associated with frontotemporal lobar degeneration (FTLD). It is an insidious disorder characterised by gradual impairment of speech and language that predates, usually by many years, the onset of more global cognitive deficits.