Progressive supranuclear palsy
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Marked atrophy of midbrain with cerebral and cerebellar atrophy. Sagittal midbrain to pons ratio = 0.11. On sagittal images it is possible to characterize the hummingbird sign.
Progressive supranuclear palsy (PSP), also known as the Steele-Richardson-Olszewski syndrome, is a neurodegenerative disease with no efficacious treatment.
Progressive supranuclear palsy typically becomes clinically apparent in the 6th decade of life, and progresses to death usually within a decade (2-17 years from diagnosis).