Progressive supranuclear palsy

Case contributed by Kewal Arunkumar Mistry
Diagnosis almost certain

Presentation

Longstanding parkinsonism.

Patient Data

Age: 75 years
Gender: Male

Marked atrophy of midbrain with cerebral and cerebellar atrophy. Sagittal midbrain to pons ratio = 0.11. On sagittal images it is possible to characterize the hummingbird sign. 

Case Discussion

Progressive supranuclear palsy (PSP), also known as the Steele-Richardson-Olszewski syndrome, is a neurodegenerative disease with no efficacious treatment. 

Progressive supranuclear palsy typically becomes clinically apparent in the 6th decade of life, and progresses to death usually within a decade (2-17 years from diagnosis).

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