Prostate cancer staging (F-18 PSMA PET-CT)

Case contributed by David Little
Diagnosis almost certain

Presentation

Prostate cancer high risk patient. Staging prior to radical treatment.

Patient Data

Age: 60 years
Gender: Male

F-18 PSMA PET-CT

Nuclear medicine

There is marked focal PSMA uptake in the right side of the prostate corresponding to the primary tumor. There is a 10 mm mildly PSMA avid right pelvic sidewall lymph node which is likely involved. No nodal or metastatic disease elsewhere.

Case Discussion

F-18 PSMA is useful in the staging of high risk prostate cancer patients being considered for radical therapy. 

F-18 PSMA has been shown to have a higher diagnostic accuracy for primary staging compared with CT and bone scan (92% vs 65% respectively), a greater treatment impact (28% vs 15% respectively) and fewer uncertain results (7% vs 23% respectively) 1.

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