Two specimens submitted for analysis:
1. Section shows a moderately cellular tumour comprising astrocytes showing hyperchromatic nuclei, moderate nuclear pleomorphism and ill-defined eosinophilic cytoplasm. Mitotic activity is not seen. Rosenthal fibres or eosinophilic granular bodies are not identified. There is no necrosis or microvascular proliferation.
2. Section shows one fragment of cortex with infiltration by a tumour with appearances similar to those seen in specimen 1. A Ki-67 stain shows a proliferative index of approximately 10%. Based on the material received, the features are consistent with a low grade glioma.
Features consistent with a low grade glioma and most in keeping with a protoplasmic astrocytoma.
features images from this case