Pseudomembranous (Clostridium difficile) colitis: toxic megacolon

Case contributed by Dr Chris O'Donnell


On oral antibiotics. Unwell with abominal pain, diarrhoea and bleeding. Not getting better.

Patient Data

Age: 40
Gender: Female

Gross oedema of the left hemicolonic wall with marked proximal colonic distension.  Note surrounding inflammation with signs of low serum albumin including marked subcutaneous oedema on CT. There are multiple enlarged mesenteric lymph nodes. Patient is unwell with poor nutrition and colonic dilatation = toxic megacolon. Clostridium difficile cultured in faeces.


Scan performed 1 week prior to the above examination

One week prior had less marked oedema of left hemicolonic wall, no proximal colonic dilatation, and no signs of poor nutrition including subcutaneous oedema.

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Case information

rID: 17548
Published: 25th Apr 2012
Last edited: 16th Oct 2015
Inclusion in quiz mode: Included

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