Pseudomembranous colitis

Case contributed by Jeremy Jones
Diagnosis probable


Abdominal pain and diarrhea.

Patient Data

Age: 70 years
Gender: Male

Admission plain film




Pancolitis with minimal pericolonic fat stranding or free fluid.

Case Discussion

Pancolitis with a history of diarrhea and no PR bleeding is highly suggestive of an infective etiology.  While other differentials of colitis should be considered, infection (particular C. diff.) needs to be actively excluded.

The stool was proven to contain C. difficile toxin and oral (via PEG tube) antibiotics (vancomycin) started.  It is worth noting that the antibiotic therapy must be administered by the oral route in order to be effective.

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