Pulmonary fibrosis, infection and primary lung cancer

Case contributed by Prof Oliver Hennessy


Known pulmonary fibrosis for 3 years. Recent deterioration with raised inflammatory markers. Probable pneumonia.

Patient Data

Age: 75 years
Gender: Male

There are changes of diffuse and extensive fibrosis in both lungs. Segmental area of consolidation is present in the left upper lobe. An ill defined possible mass lesion is seen at the right base

CT confirms the findings of diffuse and extensive pulmonary fibrosis/UIP pattern

There is an area of consolidation in the left upper lobe, this is most likely due to infection

A mass lesion is seen in the right lower lobe, this is suspicious for a primary lung cancer. This mass was not present on previous CT studies. Some enlarged mediastinal nodes are present.

Case Discussion

The CT findings are characteristic of IPF/UIP pattern.

Lung carcinoma occurs in 5%-15% of patients with IPF, the majority of cancers occur in the lower lobes, peripherally situated and maybe easily be overlooked when they occur in an area of honeycomb formation.

Previous imaging, if and when available, is most useful.

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Case information

rID: 33300
Published: 7th Jan 2015
Last edited: 15th Jan 2019
System: Chest
Inclusion in quiz mode: Included

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