Pulmonary fibrosis: UIP

Case contributed by Prof Oliver Hennessy


Increasing shortness of breath in an elderly patient.

Patient Data

Age: 77
Gender: Male

CT Chest

There are changes of diffuse and extensive reticulation present in an apicobasal distribution in both lungs. There are changes of honeycomb formation at both bases.

The mediastinum is normal, there are no enlarged mediastinal nodes. No pleural calcification is seen.

No mass lesions are seen.

Case Discussion

The findings are characteristic of pulmonary fibrosis with diffuse reticulation bilaterally and honeycomb formation of a usual interstitial pneumonia (UIP) pattern, particularly at both lung bases.

There was no evidence to suspect prior asbestosis exposure; both pleura are normal with no calcified or noncalcified plaques visualised.

There is an increased incidence of lung cancers in patients with pulmonary fibrosis, and these tumours may be overlooked when there is dense basal fibrosis present

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Case information

rID: 34673
Case created: 4th Mar 2015
Last edited: 15th Jul 2017
System: Chest
Inclusion in quiz mode: Included

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