Pulmonary Langerhans cell histiocytosis
Citation, DOI, disclosures and case data
At the time the case was submitted for publication Liz Silverstone had no financial relationships to ineligible companies to disclose.View Liz Silverstone's current disclosures
Prior pleurodesis for pneumothorax in ex-smoker.
Loading Stack -
0 images remaining
numerous irregular rounded cysts with upper zone peribronchial predominance and sparing the costophrenic and anterior angles
high-attenuation pleural thickening bilaterally due to VATS pleurodesis
no bone lesions
Typical history and features of inactive pulmonary Langerhans cell histiocytosis (PLCH), an inhalational lung disease. Bronchial wall destruction and bronchial dilatation is responsible for the appearance and location of the cysts. Nodules are a feature of active inflammation of the bronchial walls and are not present in this case.
Smoking cessation is the mainstay of disease control and serial follow-up with pulmonary function tests +/- CT may be helpful.
- Castoldi M, Verrioli A, De Juli E, Vanzulli A. Pulmonary Langerhans Cell Histiocytosis: The Many Faces of Presentation at Initial CT Scan. Insights Imaging. 2014;5(4):483-92. doi:10.1007/s13244-014-0338-0 - Pubmed