Radiation-induced esophageal stricture

Case contributed by Johnathan Azar
Diagnosis almost certain

Presentation

Progressive dysphagia with history of aspiration pneumonia status-post radiation therapy for nasopharyngeal carcinoma 38 years ago. Weight loss and temporal wasting are noted. Outside examinations demonstrated no recurrence of cancer.

Patient Data

Age: 70 years
Gender: Male

There is a short segment narrowing (3 mm AP) at the level of the cricopharyngeus muscle at C5-C6 with minimal contrast passing through and associated prevertebral soft tissue thickening. Aspiration is marked by barium passing the level of the vocal folds. 

Annotated image

There is a short segment narrowing (3 mm AP) at the level of the cricopharyngeus muscle at C5-C6 (blue arrow) with minimal contrast passing through and associated prevertebral soft tissue thickening. Aspiration (yellow arrow) is marked by barium passing the level of the vocal folds. 

Case Discussion

This case demonstrates esophageal stricture most likely due to radiation therapy based on this patient’s prior examinations showing no recurrence of cancer. Complications of an esophageal stricture include perforations, weight loss, and aspiration which may all be life-threatening.

This case was co-authored by:
Noelani Gonzales, MS4
Nova Southeastern University

This case was submitted with supervision and input from:
Mudassir Syed, D.O. (Resident Radiologist)
Mayo Clinic, Jacksonville
Department of Diagnostic and Interventional Radiology

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