Rasmussen encephalitis

Case contributed by Dr Sepehr Haghighi


Intractable seizures.

Patient Data

Age: 21 months
Gender: Male

Diffuse left sided hemiatrophy with encephalomalacia and gliotic changes are seen. Severe left ex vacuo ventriculomegaly is also noted. Overlying cranial bone has normal thickness.

These changes are in-keeping with Rasmussen encephalitis.

Case Discussion

Chronic focal encephalitis (Rasmussen encephalitis) is a chronic inflammatory disease of unknown origin, usually affecting one cerebral hemisphere.  It can occur in children under 10 years 1. The patients referred with epilepsia partialis continua or generalized status epilepticus 2.

The main differential diagnoses to be considered include:

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Case information

rID: 64812
Published: 12th Jan 2019
Last edited: 12th Jan 2019
Inclusion in quiz mode: Included
Excluded from licensing
Institution: Children's medical center

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