Pituitary lesion - spontaneous regression

Case contributed by Frank Gaillard
Diagnosis almost certain

Presentation

Known right-sided pituitary lesion, stable for 4 years. Followup.

Patient Data

Age: 25 years

The non-enhancing nodule/cyst centered on the right side of the pituitary gland is stable in size. The intrinsic T1 signal has degraded, with the nodule now approximating CSF intensity.

The infundibulum demonstrates mild stable leftward deviation.

Once again, the optic chiasm and cavernous sinuses lie within normal limits.

3 years later

mri

The non-enhancing T1 hypointense ovoid nodule, centered in the right side of the pituitary gland, has significantly reduced in size.

The infundibulum demonstrates mild stable leftward deviation/angulation. Once again, the optic chiasm and cavernous sinuses lie within normal limits.

The remainder of the study is unremarkable.

5 years later

mri

The previously described right-sided pituitary cyst/nodule has completely resolved, with the pituitary appearing now normal, with only minimal residual leftward deviation of the infundibulum.

Case Discussion

This lesion either represents a Rathke's cleft cyst or a necrotic microadenoma.

Spontaneous and complete resolution of Rathke's cleft cysts is uncommon but certainly reported 1.  

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