Renal osteodystrophy

Case contributed by Dr Vikas Shah


Renal failure and renal transplant. Abnormal blood biochemistry.

Patient Data

Age: 45 years
Gender: Male
Nuclear medicine

Bone scan

The bone scan shows increased tracer uptake at the end plates of the vertebral bodies, but not involving the whole of the vertebral body at any level. There is uptake relating to degenerative change in the shoulders and knees but no pathological uptake elsewhere. Note the presence of kidney-shaped uptake in the right side of the pelvis, displacing the bladder to the left.


The endplates of the vertebral bodies have an increased density, giving rise to alternating bands of increased and normal density, like stripes on a rugby jersey. This is why this appearance is called the "rugger jersey spine". There is a kidney visible in the pelvis, which is a transplanted kidney.

Case Discussion

This is renal osteodystrophy. Chronic kidney disease leads to metabolic changes associated with hyperparathyroidism with abnormal bone turnover and mineralization. There is characteristic increased bone density at the vertebral endplates, secondary to increased osteoblast activity. This leads to alternating bands of increased and normal density on plain films and CT of the spine, and alternating bands of increased and normal uptake in the spine on a bone scan and the sign is called the "rugger jersey" sign. These bands are likened to the stripes of a rugby jersey.

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Case information

rID: 57722
Published: 9th Jan 2018
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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