Presentation
Right jaw swelling.
Patient Data
Age: 65 years
Gender: Female
From the case:
Renal osteodystrophy
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Axial non-contrast

- Diffuse bone sclerosis.
- Salt and pepper appearance of the skull secondary to widespread lytic lesions scattered throughout the skull bones.
- Multiple osteolytic lesions in the mandible. The largest expansile lytic lesion is seen at the right mandibular body, consistent with brown tumors.
Case Discussion
The patient had a history of renal failure and dialysis. Now she complained of right mandibular swelling.
Renal osteodystrophy (ROD), also known as uremic osteopathy, is the constellation of musculoskeletal abnormalities that occur in patients with chronic renal failure, due to concurrent and superimposed:
- osteomalacia (adults) / rickets (children)
- secondary hyperparathyroidism: abnormal calcium and phosphate metabolism
- bone resorption
- osteosclerosis
- soft tissue and vascular calcifications
- brown tumors