Renal osteodystrophy and brown tumors

Case contributed by Frank Gaillard


Chronic renal failure.

Patient Data

Age: Adult
Annotated image

Plain X-ray hands of a young patient with CRF shows signs of secondary hyperparathyroidism:

  • irregular, frayed and ill-defined cortical outline, pronounced at radial aspect of middle phalanges –> subperiosteal bone resorption
  • multiple lytic expansile lesions –> brown tumors (arrows)
  • osteosclerosis
  • accentuated trabecular pattern non-essential trabeculae are resorbed; those that remain appear prominent)

Case Discussion

Renal osteodystrophy is a constellation of musculoskeletal abnormalities that occur in patients with chronic renal failure.

Manifestations include:

Comment: Subperiosteal bone resorption is the hallmark of HPTH and is first identified in hands.

Credit: Dr Ahmed Haroun

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.