Retroperitoneal tuberculosis resulting in renal obstruction

Case contributed by Dr Michael P Hartung


African patient with right flank pain.

Patient Data

Age: 30 years
Gender: Female

Moderate hydronephrosis of the right kidney due to ureteral obstruction by retroperitoneal soft tissue mass along the rightward aspect of the aorta.

IVC not well seen, either compressed or invaded by mass. Bilateral common iliac DVT. 

Few prominent right common iliac lymph nodes. 


6 months after treatment

Resolved right hydronephrosis with new moderate right renal atrophy. Mild post inflammatory/infectious thickening of proximal right ureter. 

Persistent but decreased size of right periaortic retroperitoneal mass. IVC remains poorly seen and is likely compressed by mass. Resolved common iliac DVT. 

Case Discussion

The differential diagnosis for this case would include retroperitoneal fibrosis, lymphoma, IVC leiomyosarcoma, lymphoma, and TB. TB was confirmed with biopsy after the original CT and the patient underwent therapy, with resolved hydronephrosis on 6-month follow up imaging. While not a common diagnosis in the developed world, it should come to mind whenever dealing with an unknown mass or unusual pathology in the developing world. 

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Case information

rID: 60321
Published: 16th May 2018
Last edited: 19th May 2018
Inclusion in quiz mode: Included

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