Reversal sign

Case contributed by Sammy Tawk
Diagnosis certain

Presentation

Unconscious patient after resuscitation following cardiac arrest.

Patient Data

Age: 55 years
Gender: Male
ct

Inversion of the attenuation between white and grey matter, the latter showing lower attenuation compared to the white matter (normally its attenuation is higher).

Case Discussion

The reversal sign is seen on non-enhanced brain CT scan due to diffuse anoxic brain injury. Its pathogenesis is complex and not fully understood with multiple factors being implicated.

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