Reversible basal ganglia T1 hyperintensity

Case contributed by Dr Andrew Lawson


Farmer exposed to chemicals, developed fulminant hepatitis, became encephalopathic. Subsequently suffered from decline in cognition.

Patient Data

Age: 60-65
Gender: Male

Bilateral symmetrical increased T1 signal seen in globus pallidus and substantia nigra.


2 years later MRI for follow up

Resolution of basal ganglia hyperintensity.

Case Discussion

Presumed metal deposition in from acquired hepatocerebral degeneration resulting in high T1 on the initial scan.

Two years later, patient develops progressive cognitive decline, but interestingly resolution of signal in lentiform nucleus.

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Case information

rID: 25621
Published: 31st Oct 2013
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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