SAPHO syndrome

Case contributed by Liz Silverstone


Severe left anterior chest pain for 4 weeks, now resolving. History of psoriasis.

Patient Data

Age: 55 years
Gender: Female

Ill-defined increased attenuation over the first left costochondral junction.


Expanded anterior left first rib with peripheral calcification of the costal cartilage and sclerosis extending into the bone.

Areas of bone sclerosis around the xiphisternal and manubriosternal joints and in the anterior corners of T6 -T10 and L2 vertebral bodies.

Case Discussion

Normal sacroiliac joints on subsequent MR scan.

The Rheumatologist diagnosed SAPHO syndrome. The presentation, imaging appearances and sites of involvement are characteristic.

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