Patient Data
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Chest x-ray demonstrates upper zone reticulonodular opacities with extensive mediastinal and hilar nodal enlargement. Stage II sarcoidosis with both nodal and parenchymal disease.
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CT of the chest demonstrates diffuse areas of nodularity predominantly in a peribronchial distribution with patchy areas of consolidation particularly in the upper lobes. There is some surrounding ground glass opacities. No gross reticular changes to suggest fibrosis.
Marked mediastinal and perihilar adenopathy is present.
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Xray 3 years later demonstrates some reduction on nodal enlargement.
Case Discussion
This patient had established sarcoidosis both clinically and on the basis of bronchial biopsy.
Histology
Several multinucleated giant cells identified in a chronic inflammatory, non-necrotizing background; observations are consistent with sarcoidosis.
Final diagnosis: sarcoidosis