Sarcoidosis

Case contributed by Assoc Prof Frank Gaillard

Patient Data

Gender: Male

Chest x-ray demonstrates upper zone reticulonodular opacities with extensive mediastinal and hilar nodal enlargement. Stage II sarcoidosis with both nodal and parenchymal disease. 

CT of the chest demonstrates diffuse areas of nodularity predominantly in a peribronchial distribution with patchy areas of consolidation particularly in the upper lobes. There is some surrounding ground glass opacities. No gross reticular changes to suggest fibrosis.

Marked mediastinal and perihilar adenopathy is present.

Xray 3 years later demonstrates some reduction on nodal enlargement.

Case Discussion

This patient had established sarcoidosis both clinically and on the basis of bronchial biopsy.

Histology

Several multinucleated giant cells identified in a chronic inflammatory, non-necrotizing background; observations are consistent with sarcoidosis.

Final diagnosis: sarcoidosis

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