Schizencephaly - bilateral open lip

Case contributed by Dr Praveen Jha


Quadriparesis recently, some mental retardation. No previous imaging.

Patient Data

Age: 20 years
Gender: Male

Grey-matter lined CSF clefts extending from pial surface to ependymal surface, with associated polymicrogyric smooth surface along clefts.  Both are open-lip. Partially deficient septum pellucidum was also suggested.

Case Discussion

This case depicts bilateral schizencephaly. An important differential is a porencephalic cyst, which is classically described as encephalomalacic cysts communicating with the ventricle. In this case, a hypointense signal cleft lining is seen along the ependymal surface, which is usually absent in porencephalic cyst.

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Case information

rID: 18533
Published: 11th Jul 2012
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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