Schizencephaly - bilateral

Case contributed by Frank Gaillard

MRI of the brain of a child demonstrating bilateral and midline abnormalities.

On both sides, abnormal grey matter (polymicrogyria) can be seen extending from the cortex to the body of the lateral ventricles. On the left, a cleft is present filled by CSF, whereas on the right only a slight indentation of the ventricular wall is present.

Additionally, the septum pellucidum is absent.

Findings are consistent with bilateral schizencephaly. On the right, it is of the closed-lip variety whereas on the left it is open-lip. 

Note: This case has been tagged as "legacy" as it no longer meets image preparation and/or other case publication guidelines.

Case Discussion

Typical appearances of schizencephaly with polymicrogyria

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