Sclerosing angiomatoid nodular transformation (SANT) - spleen

Case contributed by Dr Gustavo Aguiar


Incidental finding of a splenic mass during ovarian cyst follow-up.

Patient Data

Age: 50 years
Gender: Female

A well-circumscribed splenic mass with heterogeneous low signal intensity on T1WI, low signal on the T2WI image and mild peripheral enhancement during the arterial phase.

Case Discussion

The differential diagnosis of a splenic mass is broad and includes benign and malignant entities. Hemangiomas are the most common benign primary neoplasm of the spleen, but they have high signal intensity on T2WI. Angiosarcomas have a high T2 signal intensity too, and they often have a cystic area, which in SANT have not been reported.

Thus, a well-circumscribed splenic mass showed low signal intensity on T1 and T2WI, is suggestive of sclerosing angiomatoid nodular transformation of the spleen (SANT).

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Case information

rID: 66488
Published: 19th Mar 2019
Last edited: 14th Aug 2019
Inclusion in quiz mode: Excluded
Institution: Clínica Villas Boas

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