Presentation
Headache.
Patient Data
Leptomeningeal enhancement lining the 3rd and 4th ventricles on the right side. The lesions elicit subtle low signal on T1 WI and subtle high signal on T2 & FLAIR WI.
Bilateral cerebral subcortical white matter and deep periventricular foci and patches of abnormal signal with no contrast enhancement, representing chronic ischemic foci.
Case Discussion
The patient was known to have systemic highly aggressive lymphoma under chemo and radiotherapy, with a new-onset headache.
MRI revealed leptomeningeal enhancing lesions lining the 3rd and 4th ventricles.
CSF analysis confirmed lymphomatous infiltrations.
Secondary CNS lymphoma (SCNSL) refers to central nervous system spread of lymphoma that originated elsewhere (in contrast to primary CNS lymphoma).
Secondary CNS lymphoma more commonly involves the leptomeninges (as in our case),unlike primary CNS lymphoma,
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